王光益,张清芳,闫 杰,王玉龙,张明明,王春宝,吴松晖,龙建军.任务导向性踝关节康复机器人训练对脑卒中足下垂患者皮质激活特征的研究[J].中国康复医学杂志,2025,(4):516~521 |
任务导向性踝关节康复机器人训练对脑卒中足下垂患者皮质激活特征的研究 点此下载全文 |
王光益 张清芳 闫 杰 王玉龙 张明明 王春宝 吴松晖 龙建军 |
深圳市第二人民医院,广东省深圳市,518035 |
基金项目:河套深港科技创新合作区深圳园区项目(HTHZQSWS-KCCYB-2023060);深圳市科技计划项目(JCYJ20210324122200002);深圳市三名工程“南京医科大学励建安团队”资助项目(SZSM202111010) |
DOI:10.3969/j.issn.1001-1242.2025.04.006 |
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摘要: |
摘要
目的:采用功能性近红外光谱技术(fNIRS)研究脑卒中后足下垂患者在执行任务导向性踝关节康复机器人训练任务时的皮质激活特征。
方法:本研究纳入20例脑卒中后足下垂患者,使用51通道fNIRS系统测量患者执行任务导向性踝关节康复机器人训练时大脑皮质的HbO2情况。选择双侧背外侧前额叶(DLPFC)、初级运动皮层(M1)、初级躯体感觉皮层(S1)、运动前区和辅助运动区(pSMA)及额下回(IFG)作为本次研究的感兴趣区。数据处理和分析采用MATLAB(R2021b)和SPSS 25.0软件实现。
结果:脑卒中后足下垂患者在执行任务导向性踝关节康复机器人训练任务时,通道19、26、28、29、35、36、39、42、48被显著激活(P<0.05)。根据通道脑区对应信息,患者的双侧pSMA、双侧DLPFC、健侧S1及健侧IFG被激活。
结论:任务导向性踝关节康复机器人训练可引起脑卒中后足下垂患者大脑皮质激活增加,这可能是其在治疗脑卒中后足下垂中的潜在神经机制。 |
关键词:脑卒中 足下垂 踝关节康复机器人 任务导向性训练 功能性近红外光谱 皮质激活 |
Cortical activation characteristics in patients with post-stroke foot drop during task-oriented ankle rehabilitation robot raining Download Fulltext |
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Shenzhen Second People’s Hospital, Shenzhen, Guangdong, 518035 |
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Abstract: |
Abstract
Objective: To investigate the cortical activation characteristics of patients with post-stroke foot drop during task-oriented ankle rehabilitation robot training using functional near-infrared spectroscopy (fNIRS).
Method: Twenty patients with post-stroke foot drop were recruited. A 51-channel fNIRS system were used to measure changes in oxygenated hemoglobin (HbO2) in the cortical regions during task-oriented ankle rehabilitation robot training. The regions of interest (ROIs) included the bilateral dorsolateral prefrontal cortex (DLPFC), primary motor cortex (M1), primary somatosensory cortex (S1), premotor area and supplementary motor area (pSMA), and inferior frontal gyrus (IFG). Data processing and statistical analysis were conducted using MATLAB (R2021b) and SPSS 25.0 software.
Result: Significant cortical activation was observed in channels 19, 26, 28, 29, 35, 36, 39, 42, and 48 (P<0.05) during task-oriented ankle rehabilitation robot training in patients with post-stroke foot drop. Based on the channel-to-brain region registration, significant activation was noted in the bilateral pSMA, bilateral DLPFC, unaffected side S1, and unaffected side IFG’s area.
Conclusion: Task-oriented ankle rehabilitation robot training can lead to increased cortical activation in patients with post-stroke foot drop, which may represent a potential neural mechanism underlying its therapeutic effects. |
Keywords:stroke foot drop ankle rehabilitation robot task-oriented training functional near-infrared spectroscopy cortical activation |
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