| 王 坤,李雅薇,王玉龙.早期下肢重复性训练对急性脑梗死患者下肢功能恢复的影响[J].中国康复医学杂志,2020,(8):949~953 |
| 早期下肢重复性训练对急性脑梗死患者下肢功能恢复的影响 点此下载全文 |
| 王 坤 李雅薇 王玉龙 |
深圳大学第一附属医院(深圳市第二人民医院)
康复医学科，518035 |
| 基金项目： |
| DOI：10.3969/j.issn.1001-1242.2020.08.012 |
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| 摘要
目的：探讨早期下肢重复性训练促进急性脑梗死患者下肢功能恢复的效果。
方法：将108例符合纳入标准的急性脑梗死患者按照随机数字表法分为2组，每组54例，两组均在发病48h内给予康复训练，对照组给予常规康复训练，观察组在常规康复训练基础上给予下肢重复性训练，比较两组治疗前后脑源性神经营养因子（BDNF）、神经元特异性烯醇化酶（NSE）和神经生长因子（NGF）水平，并比较两组治疗前及治疗第4周、第8周Fugl-Meyer量表下肢运动功能、平衡功能评分和功能性步行量表（FAC）评分。
结果：治疗后两组血清BDNF、NSE水平降低（P＜0.01），观察组降低更明显（P＜0.01），两组NGF水平升高（P＜0.01），观察组升高更明显（P＜0.01），与对照组比较差异有显著性意义；治疗第4周、第8周时，观察组Fugl-Meyer运动功能、平衡功能评分显著高于对照组（P＜0.01），治疗后观察组FAC等级显著高于对照组（P＜0.05），差异均有显著性意义。
结论：早期下肢重复性训练有利于改善血清BDNF、NSE、NGF水平，促进下肢运动、平衡和步行能力的提高，治疗急性脑梗死下肢功能障碍效果显著。 |
| 关键词：下肢重复性训练 急性脑梗死 运动 平衡 步行能力 |
| Effects of early repetitive training on lower limb function recovery in patients with acute cerebral infarction Download Fulltext |
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| Department of Rehabilitation Medicine, the First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518035 |
| Fund Project: |
| Abstract: |
| Abstract
Objective：To investigate the effects of early repetitive training on lower limb function recovery in patients with acute cerebral infarction.
Method：Totally 108 patients with acute cerebral infarction meeting inclusion criteria were divided into two groups according to the digital random table method, with 54 cases in each group. The patients of two groups were given the rehabilitation training within 48h. The control group was given routine rehabilitation training, while the observation group was given repetitive training of lower limb besides the conventional rehabilitation training. Brain derived neurotrophic factor (BDNF), neuron specific enolization enzyme (NSE) and nerve growth factor (NGF) level of the two groups were compared before and after the treatment, and Fugl-Meyer scale for lower limb motor function, balance function score and functional ambulation category(FAC) scale score of the two groups were compared before treatment and after 4 or 8 weeks treatment.
Result：The serum BDNF and NSE levels of the two groups reduced after treatment (P<0.01) with more significant reduction in the observation group (P<0.01). The NGF level of the two groups increased (P<0.01) with more obvious increase in the observation group (P<0.01), compared with the control group. The Fugl-Meyer motor function and balance function score of the observation group was significantly higher than that of the control group after 4 or 8 weeks treatment (P<0.01). The FAC grade was significantly higher than that of the control group after treatment with the statistically significant difference(P<0.01).
Conclusion：Early lower limb repetitive training is effective in improving the serum BDNF, the NSE, NGF levels, promoting the lower limb movement, balance and walking ability and has significant effect in treating lower limb dysfunction for patients with acute cerebral infarction. |
| Keywords:lower extremity repetitive training acute cerebral infarction movement balance walking ability |
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