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邱丽芳,蔡扬帆,江一静,林婉卿,李秀宇.反应扩充疗法联合低频重复经颅磁刺激对脑卒中非流畅性失语的临床疗效[J].中国康复医学杂志,2020,(10):1192~1197
反应扩充疗法联合低频重复经颅磁刺激对脑卒中非流畅性失语的临床疗效    点此下载全文
邱丽芳  蔡扬帆  江一静  林婉卿  李秀宇
福建中医药大学附属康复医院言语治疗部,福建省福州市,350003
基金项目:福建省科技厅引导性项目(2019Y0041);中央引导地方科技发展专项(2018L3009)
DOI:10.3969/j.issn.1001-1242.2020.10.007
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摘要:
      摘要 目的:探讨反应扩充疗法(response elaboration training, RET)联合低频重复经颅磁刺激(rTMS)对脑卒中后非流畅性失语症患者的语言疗效。 方法:纳入2018年9月至2019年11月本院收治的60例脑卒中非流畅性失语症患者,按随机数字表法分为常规组(仅采用传统语言训练),rTMS组(传统语言训练+低频rTMS治疗),RET+rTMS组(传统语言训练+RET+低频rTMS治疗),每组各20例。所有患者治疗前和治疗4周后均进行西方失语症成套测验(WAB)与汉语标准失语症检查法(CRRCAE)动作说明、画面说明2个亚项,以及实用性语言交流能力检查(CADL)评估,并进行组间比较。 结果:治疗后,RET+rTMS组患者WAB自发言语、听理解、命名、复述、AQ得分均明显高于常规组(P<0.05),RET+rTMS组自发言语、命名及AQ得分高于rTMS组(P<0.05);治疗后,RET+rTMS组患者CRRCAE动作说明和画面说明得分均明显高于常规组和rTMS组(P<0.05),rTMS组患者动作说明得分高于治疗前(P<0.05),常规组以上两项得分与治疗前差异无显著性意义(P>0.05);治疗后,rTMS组与RET+rTMS组患者CADL得分均高于常规组(P<0.05),RET+rTMS组CADL得分高于rTMS组(P<0.05)。 结论:反应扩充疗法联合低频重复经颅磁刺激能显著改善非流畅性失语症患者的语言表达能力。
关键词:脑卒中  非流畅性失语  反应扩充疗法  低频重复经颅磁刺激
Effects of response elaboration training combined with rTMS in patients with non-fluent aphasia    Download Fulltext
Department of Speech Language Therapy, Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350003
Fund Project:
Abstract:
      Abstract Objective: To explore the therapeutic effects of response elaboration training combined with rTMS on patients with non-fluent aphasia after stroke. Method: Sixty patients with non-fluent aphasia after stroke were randomly allocated into either conventional language therapy group, rTMS group (conventional language therapy+rTMS) or rTMS+RET group (conventional language therapy +RET+rTMS), with 20 cases in each group. The language ability was evaluated by the western aphasia battery(WAB),the Chinese rehabilitation research center standard aphasia examination(CRRCAE) and communicative abilities of daily living (CADL) at baseline and four weeks after treatment. Result: After treatment, the sub-item of spontaneous speech, comprehension, repetition, naming and AQ of WAB were significantly higher in the RET+rTMS group than those in conventional group(P<0.05). The sub-item of spontaneous speech, naming and AQ in the RET+rTMS group were significantly higher than those in the rTMS group(P<0.05). After treatment, The sub-item of action naming and picture description of CRRCAE in the RET+rTMS group were significantly higher than those in the conventional group and rTMS group(P<0.05). After training, the action naming in CRRCAE was significantly higher than before training in the rTMS group(P<0.05). After treatment, the score of CADL in the rTMS group and RET+rTMS group showed significant improvement than that in the conventional group(P<0.05). Conclusion: RET combined with rTMS can improve the verbal abilities in patients with non-fluent aphasia after stroke.
Keywords:stroke  non-fluent aphasia  response elaboration training  repetitive transcranial magnetic stimulation
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