| 尹爱梅,陆 晓.脑卒中患者膈肌功能及肺功能变化的临床研究[J].中国康复医学杂志,2023,(10):1366~1371 |
| 脑卒中患者膈肌功能及肺功能变化的临床研究 点此下载全文 |
| 尹爱梅 陆 晓 |
| 南京医科大学，江苏省南京市，210029 |
| 基金项目：中国脑卒中高危人群干预适宜技术研究及推广项目（GN-2018R0010） |
| DOI：10.3969/j.issn.1001-1242.2023.10.006 |
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| 摘要： |
| 摘要
目的：观察脑卒中患者膈肌功能及肺功能的变化。
方法：筛选符合入组标准的脑卒中患者及健康受试者共60例，每组30例，收集所有受试者膈肌功能及肺功能数据，并比较两组之间的差异：使用膈肌超声评估患者平静呼吸及深呼吸膈肌厚度、膈肌活动度，并计算膈肌增厚率；行吸气肌压力检测：评估患者最大吸气压（maximum inspiratory pressure，MIP）；评估患者的肺功能：用力肺活量（forced vital capacity，FVC）、第1秒用力呼气量（forced expiratory volume in one second，FEV1）、第1秒用力呼气量/用力肺活量（forced vital capacity/forced expiratory volume in one second，FEV1/FVC）、呼气流量峰值（peak expiratory flow，PEF）。
结果：脑卒中组及健康对照组一般临床资料无显著性差异；与健康对照组相比，脑卒中组受累侧深吸气末膈肌厚度及膈肌增厚率显著下降（P＜0.01），非受累侧深吸气末膈肌厚度及膈肌增厚率明显下降（P＜0.05）；受累侧膈肌深吸气末膈肌厚度（P＜0.05）及膈肌增厚率（P＜0.01）较未受累侧下降；深呼吸时，脑卒中患者左侧膈肌活动度明显降低（P＜0.05）；脑卒中患者MIP较健康对照组显著下降（P＜0.01）；脑卒中患者FVC、FEV1、PEF较对照组均出现明显下降（P＜0.01）。
结论：脑卒中患者深呼吸时膈肌厚度、膈肌活动度和最大吸气压降低，肺功能显著下降，膈肌功能及肺功能的评估可为脑卒中患者呼吸康复训练方案的制定提供客观评估数据支持。 |
| 关键词：脑卒中 膈肌功能 肺功能 |
| The changes of diaphragm function and pulmonary function in stroke patients Download Fulltext |
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| Nanjing Medical University， Nanjing，210029 |
| Fund Project: |
| Abstract: |
| Abstract
Objective： To observe the changes of diaphragm muscle function and pulmonary function in patients with stroke.
Method： Totally 30 stroke patients and 30 healthy volunteers who meet the inclusion and exclusive criteria were selected in this study. Diaphragm muscle function and pulmonary function were measured， and were compared between the two groups： ①Diaphragm function：Diaphragm thickness and diaphragmatic excursion were measured at end expiration and at the end of deep inspiratory by ultrasonography； Inspiratory muscle pressure： maximum Inspiratory Pressure（MIP） were measured.②Pulmonary function included the forced vital capacity （FVC） and forced expiratory volume in one second （FEV1）， forced expiratory volume in the first second/forced vital capacity （FEV1/FVC）， peak expiratory flow （PEF） were recorded.
Result： There was no statistical difference in the general clinical data between the stroke group and the healthy control group； Diaphragm function：At the end of deep inspiratory， the diaphragm thickness and diaphragm thickening fraction at the stroke patients’ hemiplegic side or unaffected side were significantly decreased， diaphragm function of hemiplegia side is lower than unaffected side. And the left diaphragmatic excursion were dropped significantly in the stroke group； Inspiratory muscle pressure： MIP decreased significantly in stroke patients； Pulmonary function： FVC， FEV1 and PEF decreased significantly in stroke patients.
Conclusion： The diaphragm muscle function and pulmonary function of stroke patients were significantly decreased. The assessment of diaphragm muscle function and pulmonary function may provide evidence to support the formulation of rehabilitation training program for stroke patients. |
| Keywords:stroke diaphragm function pulmonary function |
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