| 张敬东,张新,袁绍辉,俞兴,$2.大鼠腰、颈段脊髓神经元间联系的c-fos基因研究[J].中国康复医学杂志,2006,21(7):588~ |
| 大鼠腰、颈段脊髓神经元间联系的c-fos基因研究 点此下载全文 |
| 张敬东 张新 袁绍辉 俞兴 $2 |
| [1]解放军第二零八医院骨科,长春130062 [2]吉林大学第一医院骨科,长春130062 [3]北京中医药大学东直门医院骨科,长春130062 |
| 基金项目：本课题为吉林省科委资助课题（20030509） |
| DOI： |
| 摘要点击次数: 2054 |
| 全文下载次数: 1898 |
| 摘要： |
| 目的：应用c-fos基因研究腰段和颈段脊髓神经元之间的联系。方法：成年雄性SD大鼠20只，钳夹左侧坐骨经神，灌注取材后行c-fos免疫组化染色。结果：在腰段L4-6脊髓中，钳夹诱发的c-fos基因表达均在钳夹同侧脊髓灰质内，脊髓灰质前角神经元和后角神经元中的c-fos基因表达明显增多，对照侧右侧脊髓中的神经元c-fos基因未见明显表达。在颈段C5-8脊髓中．双侧脊髓灰质前角中可见c-fos基因表达明显增多．双侧脊髓灰质后角中未见明显c-fos基因表达。结论：颈段脊髓和腰段脊髓神经元之间存在着神经纤维联系。 |
| 关键词：坐骨神经 c-fos基因 脊髓 神经元 |
| A c-fos labeling study on the neuronal pathway connection between the cervical spinal cord and the lumbar spinal cord Download Fulltext |
| ZHANG Jingdong ZHANG Xin YUAN Shaohui et al |
| Department of Orthopaedics,208 Hospital,PLA,Changchun,130062 |
| Fund Project: |
| Abstract: |
| Objective:To investigate the neuronal pathway connection between the cervical spinal cord and the lumbar spinal cord with c-fos labeling. Method: 20 male SD rats were operated to expose and grind the left sciatic nerve with forceps. The cervical and lumbar spinal cord was taken out 2 hours after the operation.Then the immunochemical labeling of the c-fos was done. Result:The anterior corner cell and posterior corner cell with c-fos labeling were found in the left lumbar spinal cord(L4-6),and it was found in the anterior corner of the two side cervical spinal cord(C5-8) too.Conclusion: There is neural pathway connection between the cervical spinal cord and the lumbar spinal cord. |
| Keywords:sciatic nerve c-fos gene spinal cord neuron |
|
| 查看全文 查看/发表评论 |
