| 刘 霞,路新国.茶多酚对运动小鼠心肌钙离子、ATP酶及自由基代谢的影响[J].中国康复医学杂志,2007,22(12):1062~1063 |
| 茶多酚对运动小鼠心肌钙离子、ATP酶及自由基代谢的影响 点此下载全文 |
| 刘 霞 路新国 |
| 上海中医药大学，上海市蔡伦路1200号，201203 |
| 基金项目： |
| DOI： |
| 摘要点击次数: 2775 |
| 全文下载次数: 2195 |
| 摘要： |
| 目的:探讨茶多酚对运动小鼠心肌组织损伤的保护作用。方法：以小鼠力竭运动为模型，观察茶多酚对心肌组织钙离子（Ca2+）含量、钠泵（Na+-K+-ATPase）和钙泵（Ca2+-ATPase）活性、丙二醛（MDA）含量、超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）和总抗氧化能力（TAC）的影响。结果:力竭运动可引起小鼠心肌组织Ca2+和MDA含量显著升高，心肌组织Ca2+-ATPase、Na+-K+-ATPase、SOD、GSH-Px和T-AOC的显著下降，而茶多酚可抑制小鼠力竭运动后心肌Ca2+和MDA含量显著升高，抑制小鼠心肌Ca2+-ATPase、Na+-K+-ATPase、SOD、GSH-Px和TAC的显著下降。结论：茶多酚可减少力竭运动后自由基对心肌组织的攻击，具有保护力竭运动后心肌的功能和防止心肌损伤的作用。 |
| 关键词：茶多酚 心肌 自由基 三磷酸腺苷酶 钙离子 力竭运动 |
| Effect of tea polypheonls on the content of Ca2+, adenosine triphosphate activity and free radical metabolism of myocardium in mice after exhaustive exercise Download Fulltext |
|
| Shanghai Traditional Chinese Medical University，201203 |
| Fund Project: |
| Abstract: |
| Objective: To study the protective function of tea polyphenols on myocardium in mice after exhaustive exercise. Method: After the model of exhaustive exercise was established, the effect of tea polyphenols to the content of Ca2+ and MDA , Ca2+-ATPase, Na+-K+-ATPase, SOD, GSH-Px and TAC in rats′ myocardium were observed. Result: Exhaustive exercise could strikingly step up the content of Ca2+ and MDA, and significantly decreased Ca2+-ATPase, Na+-K+-ATPase, SOD, GSH-Px and TAC in mice′s myocardium after exhaustive exercise. While tea polyphenols could prevent the content of Ca2+ and MDA from setting up strikingly, and also prevented Ca2+ -ATPase, Na+-K+-ATPase, SOD, GSH-Px and TAC from decreasing significantly in mice′s myocardium after exhaustive exercise. Conclusion: Tea polyphenols can reduce the free radicals′ attack to myocardium, protect the myocardial function and prevent the myocardial damage after exhaustive exercise. |
| Keywords:tea polyphenols myocardium free radical adenosine triphosphate exhaustive exercise |
|
| 查看全文 查看/发表评论 |
