| 徐 颖,马文林,李美婧,张俊蒙,赵明中,胡大一.急性冠脉综合征后抑郁情绪对生存质量的影响[J].中国康复医学杂志,2008,23(2):132~134 |
| 急性冠脉综合征后抑郁情绪对生存质量的影响 点此下载全文 |
| 徐 颖 马文林 李美婧 张俊蒙 赵明中 胡大一 |
| 上海同济大学医学院心肺血管中心，上海四平路1239号，200092 |
| 基金项目： |
| DOI： |
| 摘要点击次数: 2457 |
| 全文下载次数: 1975 |
| 摘要： |
| 目的： 调查急性冠脉综合征（ACS）患者抑郁情绪的时点患病率，了解其对患者生存质量的影响。方法：收集上海地区ACS患者454例，运用医院焦虑抑郁量表抑郁亚量表（hospital anxiety and depression scale-depression subscale, HADS-D）评分分为抑郁情绪组（HADd＞7分）和无抑郁情绪组（HADd≤7分），并使用SF-36量表评估其生存质量。结果：合并抑郁情绪患者212例，时点患病率为46.7%；两组人群血脂及炎症因子水平差异无显著性意义（P＞0.05）；抑郁组全部生存质量评分均显著低于无抑郁情绪组（P＜0.001）；HADS-D抑郁评分与患者生存质量评分显著负相关（P＜0.001）。结论：ACS后抑郁情绪较为常见，使患者生存质量明显降低。 |
| 关键词：抑郁 流行病学 生存质量 急性冠脉综合征 |
| Research on the relationship of depressive symptoms to the quality of life in patients with acute coronary syndrome Download Fulltext |
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| Heart, Lung and Blood Vessel Center, Tongji University, Shanghai, 200092 |
| Fund Project: |
| Abstract: |
| Objective：To present a general data about Chinese patients′ depressive symptoms of acute coronary syndrome(ACS), and evaluate the impact of this kind of symptoms on their quality of life（QOL）. Method： A total of 454 Chinese patients with ACS from Shanghai were enrolled. The patients′ baseline data were obtained within 1 week after hospital admission. The Chinese version of depression subscale of the Hospital Anxiety and Depression Scale（HADS-D） and SF-36 were used to assess depressive symptoms and their QOL, respectively. All the participants were divided into two main groups: HADd＞7 (n=212) and HADa≤7(n=242). Result: There were 46.7% of 454 ACS patients meeting the criteria of minor depression. The baseline characteristics, including the level of inflammatory factor and blood cholesterol, didn′t show a significant difference between two groups (P＞0.05). The participants from the group without depressive symptoms had a better QOL than depressive group（P＜0.001）. And depressive symptoms were negatively associated with QOL(P＜0.001). Logistic regression analysis didn′t suggest that inflammatory factor was an important risk factor for depressive symptoms of ACS patients. Conclusion: This study confirmed the western notion that post-ACS depressive symptoms are common psychosocial problems, which also applies to Chinese patients diagnosed with ACS. Depressive ACS patients have rather worse quality of life. |
| Keywords:depressive symptoms epidemiology quality of life acute coronary syndrome |
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