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窦祖林,欧海宁,沈建虹,袁晓峰,兰 月.超声引导下的肉毒毒素注射对脑卒中肌痉挛的效果观察[J].中国康复医学杂志,2008,23(3):219~221
超声引导下的肉毒毒素注射对脑卒中肌痉挛的效果观察    点此下载全文
窦祖林  欧海宁  沈建虹  袁晓峰  兰 月
中山大学附属第三医院,510630
基金项目:国家科技部中国芬兰政府间科技合作项目(2006DFA33290)
DOI:
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摘要:
      摘要 目的:评价超声引导下的肉毒毒素(BTXA)注射定位技术治疗脑卒中后肌痉挛的可行性及其价值。方法:选择因脑卒中致上肢或下肢痉挛患者5例,在彩色多普勒超声仪引导下,将BTXA准确注入肌肉局部。注射后佩戴抗痉挛矫形器并进行常规康复训练。在注射前、注射后2周、4周采用改良Ashworth评级(MAS)、 Fugl-Meyer 上肢功能评分、FIM自我照顾项评分、步速和步长测量进行相关评价。结果:治疗组在注射后2周、4周,肌肉痉挛的改善程度(MAS)、上肢运动功能(Fugl-Meyer评分)、与上肢相关的日常生活活动自理能力(FIM)、步长和步速的改善均优于注射前(P<0.05)。结论:采用超声引导的BTXA注射定位技术治疗脑卒中后肌痉挛,定位准确,治疗效果明显。 关键词 肌痉挛;肌肉彩色定位图;超声波引导注射;肉毒毒素A 中图分类号:R743.3, R49 文献标识码:A 文章编号:1001-1242(2008)-03-0219-03
关键词:肌痉挛  肌肉彩色定位图  超声波引导注射  肉毒毒素A
The clinical effect of ultrasound guided botulinum toxin type A(BTXA) injection in treating muscles spasticity following stroke (5 cases report)    Download Fulltext
Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630
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Abstract:
      Objective:To evaluate the feasibility and its value of ultrasound guided botulinum toxin type A(BTXA) injection technique in treating muscles spasticity following stroke.Method:Five patients with extremities spasticity following stroke were recruited in this clinical study. Under the guide of color Doppler ultrasound diagnostic apparatus, BTXA was injected into multi-points of muscles. The outcome after BTXA injection was assessed by modified Ashworth scale(MAS), Fugl-Meyer assessment-upper limb(FMA-upper limb), Motor-functional independence measurement-upper limb (mot-FIM-upper limb), and measurement of step length and velocity, at the baseline, the 2nd week, 4th week after treatment respectively.Result:Compared the scores of MAS, FMA-upper limb, FIM-upper limb, step length and velocity after 2 and 4 weeks with before treatment, there were significant differences statistically(P<0.05).Conclusion:Ultrasound guided BTXA injection technique is an accurate positioning method in using BTXA to treat extremities muscle spasticity.
Keywords:muscle spasticity  muscle color localized atlas  ultrasound guided injection  botulinum toxin type A
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