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刘铁军,赵盟杰,沙可夫,高居忠,张夏琳,米立新,李方洁.脊髓损伤患者自主神经功能障碍的临床研究[J].中国康复医学杂志,2008,23(6):513~514
脊髓损伤患者自主神经功能障碍的临床研究    点此下载全文
刘铁军  赵盟杰  沙可夫  高居忠  张夏琳  米立新  李方洁
北京康复中心神经泌尿外科,北京,100144
基金项目:首都医学科技发展基金(2005-479)
DOI:
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摘要:
      目的:通过检测健康人群和不同节段脊髓损伤患者心率变异性(HRV),探讨脊髓损伤患者是否存在自主神经的功能障碍,以及不同节段脊髓损伤患者的自主神经的功能障碍程度是否相同。方法:依据脊髓损伤节段的不同将截瘫患者分为颈段及T1-5节段脊髓损伤组11例,T6-12脊髓损伤组7例, 腰髓损伤6例; 健康体检人群19例作为正常对照组。采用短程动态记录安静状态下心电图并进行HRV分析。结果:颈段及T1-5脊髓损伤组代表交感和迷走神经张力总合的低频检测结果301.41±358.60ms2较正常人群的620.19±333.36 ms2明显降低(P<0.05),而且所有脊髓损伤组的低频/高频比值在C1-T5为1.66±1.00、T6-12为4.03±2.66、腰髓及以下为3.35±1.89,较正常人群的2.29±0.58明显异常(P<0.05),同时不同脊髓损伤组之间的检测结果不存在显著性差异(P>0.05)。结论:脊髓损伤患者存在自主神经的功能障碍,但不同节段脊髓损伤组之间的自主神经功能障碍不存在显著性差异。
关键词:脊髓损伤  自主神经功能障碍  心率变异性
Clinical study of dysautonomia in spinal cord injury patients    Download Fulltext
Beijing Rehabilitation Research Center, 100144
Fund Project:
Abstract:
      Objective: To investigate the basis of obvious dysautonomia in spinal cord injury(SCI) patients compared with healthy people and to detect the different level of dysautonomia by measuring HRV. Method: The SCI patients were divided into cervical and thoracic cord 1-5 level group(C-T5, 11 patients),under thoracic cord 6 level group(including lumbar cord, 13 patients). There were 19 healthy people in health control group. HRV were measured by Holter analytical system in the morning at silence state. Result: The result of LF test that represented the total tone of sympathesis and vagal in C-T5 group decreased significantly than that in health group(P<0.05); All the LF/HF ratio in SCI patients changed obviously than that in health group(P<0.05); At the same time there was no obvious difference between two SCI groups about HRV(P>0.05). Conclusion: There are dysautonomia in spinal cord injury patients. There are no obvious difference about dysautonomia in different level SCI patients.
Keywords:spinal cord injury  dysautonomia  heart rate variability
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