| 张 红,刘 然,刘大力,刘世文.利用PET-CT对脑卒中早期康复训练的脑皮质功能区重组研究[J].中国康复医学杂志,2009,24(3):208~212 |
| 利用PET-CT对脑卒中早期康复训练的脑皮质功能区重组研究 点此下载全文 |
| 张 红 刘 然 刘大力 刘世文 |
| 大连大学附属中山医院,大连市解放街6号，116001 |
| 基金项目： |
| DOI： |
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| 摘要： |
| 目的：探讨脑卒中早期康复训练后脑功能区重组的规律。方法：发病1个月内的脑卒中偏瘫患者8例志愿者分为两组：康复治疗组6例，康复治疗时间1个半月，对照组2例(因个人经济原因未能接受康复治疗)；发病初和1个月末分别进行PET-CT扫描、 Fugl-Meyer评价、Barthel指数及神经功能缺损的测定。结果：8例脑卒中患者第一次扫描的健侧与患侧总均值有显著性差异（P<0.01），主要为初级运动区(M1)、后顶叶皮质(PPC)、小脑、辅助运动区(SMA)（P<0.01），治疗组与对照组无明显差异（P>0.05）；两次同侧比较，健侧总均值与治疗组第二次有明显差异（P<0.05）；患侧总均值与治疗组第二次有显著性差异（P<0.01）。第二次各组内两侧比较，治疗组均有显著性差异（P<0.01）；对照组有明显差异（P<0.05）；第二次两组间比较：健侧各功能区有明显差异（P<0.05），而两组患侧除M1无明显差异（P>0.05）外，其余各功能区有明显差异（P<0.05）。结论：卒中早期以健侧半球代偿为主导, 运动相关区在皮质功能重组中异常活跃, 脑卒中康复治疗后皮质激活区有向患侧半球转移的趋势，功能训练有利于皮质功能重组。 |
| 关键词：功能重组 脑卒中 正电子发射断层扫描仪 |
| A study on cortex function regions reorganization by PET-CT in early rehabilitation training after stroke Download Fulltext |
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| Dept. of Physical Medicine and Rehabilitation,Zhongshan Hospital Affiliated to Dalian University,Dalian,Liaoning, 116001 |
| Fund Project: |
| Abstract: |
| Objective:To explore the regularity of cortex function regions reorganization in stroke patients after early rehabilitation training. Method: Eight stroke patients with hemiplegia within one month were. divided into 2 groups:6 cases in rehabilitation training group received 1 and half months training, 2 cases in control group(no training because of economy cause). In early stage and 1 month after stroke, all patients were examined with PET-CT scanning and Fugl-Meyer、Barthel Index and lesion of brain function assessment respectively. Result:There were significant differences in general average values between affected and unaffected hemispheres in the 8 patients in the 1st PET-CT scanning(P＜0.01),mainly in M1、PPC、cerebellum and SMA(P＜0.01),but no significant difference between training group and control group(P＞0.05). Comparing the 1st and 2nd scanning in the same hemisphere,there was significant difference of general average value. between unaffected side scanning and the 2nd scanning in training group（P<0.05）, and also in affectedside（P<0.01）. Comparing affected and unaffected memisphere in the 2nd scanning,there were significant differences in training group（P<0.01） and control group（P<0.05）.In the 2nd scanning between two groups,there were significant differences in cortex function regions of unaffected hemisphere（P<0.05）,but signifcomt differences in affected hemisphere between two groups(P<<0.05) except M1(P＞0.05).Conclusion: Unaffected hemisphere plays compensation role in early period of stroke,movement-relative regions are extremely activated in cortex function reorganization.After rehabilitation treatment,activated cortex regions show a shifting trend to affected hemisphere and function training is beneficial for cortex function reorganization. |
| Keywords:function reorganization stroke positron emission computed tomography |
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