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韩彤立,邹丽萍,郑 华,伍 云,申昆玲,吕忠礼.粗大运动功能分类系统和痉挛型脑性瘫痪儿童高危因素相关性分析[J].中国康复医学杂志,2009,24(7):607~609
粗大运动功能分类系统和痉挛型脑性瘫痪儿童高危因素相关性分析    点此下载全文
韩彤立  邹丽萍  郑 华  伍 云  申昆玲  吕忠礼
首都医科大学附属北京儿童医院神经内科与康复中心,北京,100045
基金项目:美国亚利桑那州科研基金(Y410503);国家科委国际合作项目(2008DFA31850);北京市科委国际合作项目(2007G05);北京市中医药科技项目(JJ2005-17)
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摘要:
      目的:探讨粗大运动功能分类系统(GMFCS)与痉挛型脑性瘫痪儿童高危因素的相关性。方法:收集2004年2月—2007年2月于北京儿童医院神经康复中心治疗的116名痉挛型脑瘫儿童的基本信息和高危因素,应用GMFCS对粗大运动能力进行分级。使用多元逐步回归方法进行相关性分析。结果:116例痉挛型脑性瘫痪儿童中孕龄<37周的早产儿70例(62.5%),<2500g的低出生体重60例(54.5%),出生窒息46例(39.7%),孕期感染27例(23.3%),双胎16例(13.8%),早产合并低出生体重为进入回归方程的变量,回归方程有意义(P<0.001)。结论:早产合并低出生体重与GMFCS相关,更倾向于发展为GMFCSⅢ。出生窒息、孕期感染和双胎与GMFCS无关。
关键词:脑性瘫痪  高危因素  粗大运动功能分类系统
The relationship between gross motor function classification system and risk factors in spastic cerebral palsy children    Download Fulltext
Beijing Children′s Hospital Affiliated to Capital Medicine University, Beijing,100045
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Abstract:
      Objective: To investigate the relationship between gross motor function classification system(GMFCS) and risk factors in spastic cerebral palsy children.Method: The basic information and risk factors in 116 spastic cerebral palsy children were collected. GMFCS was used to define the classification for gross motor function. Step wise regression was used to analyse the relationship between GMFCS and risk factors. Result: Among the 116 cases of spastic cerebral palsy, 70 cases (62.5%) were preterm (gestational age,GA<37 weeks); 60 cases (54.5%) had low birth weight (<2500g); 46 cases (39.7%) had asphyxia at birth; 27 cases (23.3%) had infections during pregnancy; and 16 cases(13.8%) were twins. Preterm and low birth weight were the variables included by regression equation(P<0.001). Conclusion: Preterm and low birth weight correlate with GMFCS and could be more likely to be GMFCSⅢ. Asphyxia at birth, infection during pregnancy and twins do not correlate with GMFCS.
Keywords:cerebral palsy  risk factor  gross motor function classification system
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