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唐 可,倪家骧,武百山,何明伟,杨立强.连续硬膜外腔镇痛联合胶原酶溶解术治疗腰椎间盘突出症疗效分析[J].中国康复医学杂志,2009,24(10):903~905
连续硬膜外腔镇痛联合胶原酶溶解术治疗腰椎间盘突出症疗效分析    点此下载全文
唐 可  倪家骧  武百山  何明伟  杨立强
首都医科大学宣武医院疼痛诊疗科,北京,100053
基金项目:
DOI:
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摘要:
      目的:探讨连续硬膜外腔镇痛联合胶原酶溶解术治疗腰椎间盘突出症的临床疗效。方法:64例腰椎间盘突出症患者,随机分为2组:A组连续硬膜外腔镇痛组(33例),B组连续硬膜外腔镇痛术后联合盘外胶原酶溶解术(31例)。治疗后1周、6个月、12个月对两组患者疗效进行随访。结果:两组治疗后1周、6个月、12个月VAS值均较治疗前明显降低(P<0.01),JOA值均较治疗前明显提高(P<0.01)。B组治疗后12个月VAS值、JOA值较A组明显改善(P<0.05)。A组治疗后12个月优良率为81.8%,B组治疗后12个月优良率为93.5%,B组治疗后12个月疗效优于A组。结论:连续硬膜外腔镇痛联合胶原酶溶解术治疗腰椎间盘突出症远期疗效优于连续硬膜外腔镇痛组。
关键词:连续硬膜外腔镇痛  腰椎间盘突出症  胶原酶溶解术  盘外置管法
Clinical report of continuing epidural anesthesia combined with chemonucleolysis with collagenase for treating patients with lumbar disc herniation    Download Fulltext
Department of Pain Management, Xuanwu Hospital, Capital Medical University, Beijing ,100053
Fund Project:
Abstract:
      Objective: To explore the clinical effect of continuing epidural anesthesia combined with chemmonucleolysis with collagenase for treating patients with lumbar disc herniation. Method: Sixty-four patients with lumbar disc herniation were randomly divided into anesthesia group( 33 cases) and combining group( 31 cases). The effect was assessed by 1 week,6 months,12 months after treatment. Result: By 1 week, 6 months and 12 months after treatment, the value of VAS in two groups were remarkably lower than before treatment (P<0.01). Meanwhile, the value of JOA in two groups improved significantly than before treatment (P<0.01). Compared with group A, scores of VAS and JOA in group B improved significantly after treatment (P<0.05).The excellent and good rates of therapy at 12 months were 81.8 % in group A and 93.5% in group B.Group B was proved to gain better effect than group A. Conclusion: By continuing epidural anesthesia combined with collagenase with LDH, the long-term effect of therapy of combining group was better than simply anesthesia group .
Keywords:continuing epidural anesthesia  lumbar disc herniation  chemmonucleolysis with collagenase  catheterizing outside disc
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