| 李玄英,倪家骧,杨立强,武百山,何明伟,张秀双,马 玲.半月神经节联合射频治疗三叉神经痛的临床研究[J].中国康复医学杂志,2011,26(3):240~244 |
| 半月神经节联合射频治疗三叉神经痛的临床研究 点此下载全文 |
| 李玄英 倪家骧 杨立强 武百山 何明伟 张秀双 马 玲 |
| 首都医科大学附属宣武医院，北京，100053 |
| 基金项目：首都医学发展科研基金（2005-2049） |
| DOI： |
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| 摘要： |
| 摘要
目的：观察CT引导下半月神经节脉冲射频联合连续射频治疗三叉神经痛的临床效果。
方法：90例原发性三叉神经痛患者随机分为对照组（CRF组，单纯采用75℃连续射频进行治疗，N=45）和联合射频组（采用42℃脉冲射频和75℃连续射频进行治疗，CRF+PRF组，N=45），比较治疗前、治疗后1d、3d、7d、3个月、6个月、1年、2年的视觉模拟评分（VAS）、疼痛缓解率，以及治疗前、治疗后3个月、6个月、1年、2年的生存质量评分（QOL）、麻木评分和并发症发生率。
结果：治疗后两组患者的VAS评分均较治疗前明显降低（P<0.05），随访2年两种方法治疗的有效率均达100%（P>0.05）；治疗后7d 联合射频组的VAS显著低于CRF组（P<0.05），但治疗后2年联合射频组的VAS评分较对照组明显增高（P<0.05）；治疗后2年联合射频组的麻木发生率和麻木评分均较对照组明显降低（P<0.05）。
结论：半月神经节脉冲射频联合连续射频可有效缓解三叉神经痛，尽管短期疗效超过了连续射频，但长期疗效低于连续射频，并发症的发生率明显低于连续射频。 |
| 关键词：半月神经节 脉冲射频 连续射频 三叉神经痛 |
| The efficacy of gasserian ganglion combined radiofrequency treatment on trigeminal neuralgia Download Fulltext |
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| Department of Pain Medicine, Xuanwu Hospital, Capital Medical University, Beijing，100053 |
| Fund Project: |
| Abstract: |
| Abstract
Objective：To investigate the efficacy of CT-guided gasserian ganglion pulsed radiofrequency combined with continuous radiofrequency treatment on trigeminal neuralgia.
Method：Ninety patients diagnosed as idiopathic trigeminal neuralgia were randomly divided into control group (CRF group, treated with 75℃ continuous radiofrequency only, N=45) and study group（CRF+PRF group，treated with 42℃ pulsed radiofrequency and 75℃ continuous radiofrequency，N=45）. Assessments of visual analogue scale (VAS) and pain remission rate were administered before and 1d, 3d, 7d, 3 months, 6 months, 1 year and 2 years after the treatment. Patient's quality of life(QOL) was assessed by EQ-5D questionair, numbness score and the incidence of other complications were assessed before and 3 months, 6 months, 1 year and 2 years after the treatment.
Result：After the treatment, VAS scores of both groups decreased significantly compared to those before treatment(P<0.05). During 2-year follow-up, the effective rates of two methods both achieved 100% (P>0.05). VAS in CRF + PRF group was significantly lower at 7-day follow-up (P<0.05), but was significantly higher at 1-year follow-up, when compared with CRF group (P<0.05). At 2-year follow-up, the incidence and score of numbness in CRF + PRF group were significantly lower than those in control group(P<0.05).
Conclusion：Gasserian ganglion pulsed radiofrequency combined with continuous radiofrequency treatment can effectively relieve trigeminal neuralgia. Despite the long-term efficacy of combined radiofrequency treatment is not better than pure continuous radiofrequency treatment, but the incidence of complications is significantly lower than that in CRF group. |
| Keywords:gasserian ganglion pulsed radiofrequency continuous radiofrequency trigeminal neuralgia |
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