| 刘 霞,李素云,周春仙.茶多酚对急性运动后大鼠骨骼肌组织损伤的保护作用[J].中国康复医学杂志,2011,26(5):455~458 |
| 茶多酚对急性运动后大鼠骨骼肌组织损伤的保护作用 点此下载全文 |
| 刘 霞 李素云 周春仙 |
| 上海中医药大学，201203 |
| 基金项目： |
| DOI： |
| 摘要点击次数: 2465 |
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| 摘要： |
| 摘要
目的:探讨茶多酚对急性运动后大鼠骨骼肌组织损伤的保护作用。
方法：30只SD大鼠分为对照组（A）、运动组（B）和运动加茶多酚组(C)，建立力竭运动模型，1周后测试骨骼肌组织钙离子（Ca2+）含量、钠泵（Na+-K+-ATP酶）和钙泵（Ca2+-ATP酶）活性，以及在电镜和光镜下观察腓肠肌的形态和超微结构的变化。
结果:运动组与对照组相比,骨骼肌组织Ca2+含量显著升高(P<0.05)，Ca2+-ATP酶和Na+-K+-ATP酶的显著下降(P<0.05)，运动加茶多酚组与运动组相比,骨骼肌Ca2+含量显著减少(P<0.05)，Ca2+-ATP酶活性有上升趋势，Na+-K+-ATP酶活性显著升高(P<0.05)。光镜和电镜观察运动组有明显的形态学变化和超微结构的损伤，运动加茶多酚组的超微结构损伤有明显改善。
结论：茶多酚可降低急性运动后骨骼肌组织中钙离子的含量，修复骨骼肌组织的损伤。 |
| 关键词：茶多酚 骨骼肌 三磷酸腺苷酶 钙离子 组织结构 力竭运动 |
| The protective effects of tea polyphenol on rats' skeletal muscle tissue injury caused by acute exercise Download Fulltext |
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| Dept. of Nutrition, Shanghai Traditional Chinese Medical University,201203 |
| Fund Project: |
| Abstract: |
| Abstract
Objective: To approach the protection effects of tea polyphenol on rats' skeletal muscle tissue injury caused by acute exercise.
Method：Thirty rats were randomly divided into 3 groups, control group(A), exercise group (B) and exercise with tea polyphenol group(C). The rat model of acute exhausted exercise was established. One week later the content of Ca2+, the activities of Na+-K+-ATPase and Ca2+-ATPase in skeletal muscles were measured, and the changes of morphology and altrastructure of gastrocnemius were observed under optical and electric microscopes.
Result: Compared with A group, the content of Ca2+ increased(P<0.05),activities of Ca2+-ATPase and Na+-K+-ATPase dropped(P<0.05) in B group. Compared with B group, the content of Ca2+ decreased(P<0.05), actrivity of Ca2+-ATPase had rising tendency and activity of Na+-K+-ATPase rose(P<0.05) in C group. Evident morphological changes and ultrastructure injury were observed in B group, but in C group ultrastructure injury was lighter than those in B group.
Conclusion: Tea polyphenol can reduce the content of Ca2+ in skeleton muscles after acute exercise and repair the skeletal muscle tissue injury caused by acute exercise. |
| Keywords:tea polyphenol skeletal muscle Adenosine triphosphatase tissue structure exhaustive exercise |
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