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陶涛涛,林海燕,屠文展,刘怀霞,程 博,庄进飞,蒋松鹤.水中活动平板训练对脊髓损伤大鼠体感、运动诱发电位及运动功能的影响[J].中国康复医学杂志,2011,26(11):1020~1024
水中活动平板训练对脊髓损伤大鼠体感、运动诱发电位及运动功能的影响    点此下载全文
陶涛涛  林海燕  屠文展  刘怀霞  程 博  庄进飞  蒋松鹤
温州医学院附属第二医院康复理疗中心,温州,325027
基金项目:温州市科技局资助项目(Y20090197)
DOI:
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摘要:
      摘要 目的:探讨水中平板训练对脊髓损伤(SCI)大鼠体感诱发电位(SEP)、运动诱发电位(MEP)及运动功能的影响。 方法:将成年雄性SD大鼠25只,随机分为假模组、模型对照组、水疗训练组、减重平板训练组和水中平板训练组。采用改良Allen's打击法制作T10—11 SCI模型,采用BBB评分、爬网格实验、SEP及MEP评定肢体功能及训练效果。 结果:BBB评分及爬网格实验显示,水中平板训练组的大鼠后肢运动功能较其他组明显改善(P<0.05)。SEP、MEP的潜伏期,三组训练组较模型对照组均有显著缩短(P<0.05);但三组训练组之间MEP潜伏期差异无显著性意义(P>0.05)。水中平板训练组较减重平板训练组SEP、MEP波幅明显增大,差异均有显著性意义(P<0.05)。 结论:三组训练对脊髓损伤大鼠SEP、MEP及运动功能均有不同程度的促进恢复作用,其中水中平板训练最为显著。
关键词:脊髓损伤  运动诱发电位  体感诱发电位  水中活动平板训练
The effect of underwater treadmill training on somatosensory evoked potential, motor evoked potential and locomotive functional recovery in rats following spinal cord injury    Download Fulltext
Rehabilitation and Physical Medicine department of 2nd affiliated hospital of Wenzhou Medical College, Wenzhou, 325027
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Abstract:
      Abstract Objective: To provide experimental evidences for the effectiveness of underwater treadmill training on somatosensory evoked potential(SEP), motor evoked potential(MEP) and locomotive functional recovery in rats following spinal cord injury (SCI). Method: A total of 25 Sprague Dawley rats were randomly divided into five groups: sham group, control group, hydrotherapy training group, body weight supported treadmill training group and underwater treadmill training group. SCI model was performed by generating a contusion at T10 segment with the modified Allen's punch method. In this study, Basso, Beattie, and Bresnahan (BBB) locomotor rating scale, climbing test, SEP and MEP were used to investigate hindlimb function recovery. Result: The BBB locomotor rating scale and climbing test showed, locomotor recovery improved more significantly in underwater treadmill training group than that in hydrotherapy training group and body weight supported treadmill training group (P<0.05). The latencies of SEP and MEP in three rehabilitation groups decreased obviously compared with that in control group (P<0.05), but there was no significant difference among the latencies of MEP in three rehabilitation groups(P>0.05). The wave amplitude of SEP and MEP in underwater treadmill training group increased obviously compared with that in body weight supported treatmill training group,there was significant difference between the two rehabilitation groups(P<0.05). Conclusion: Three kinds of rehabilitation training all can promote the improvements of SEP,MEP and locomotive function, the underwater treadmill training group is the best one among three rehabilitation groups.
Keywords:spinal cord injury  motion evoked potential  somatosensory evoked potential  underwater treadmill training
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