| 宋 红,邓景贵,陶 希,陈美娟.踏车运动对老年稳定型心绞痛患者的影响[J].中国康复医学杂志,2011,26(12):1140~1143 |
| 踏车运动对老年稳定型心绞痛患者的影响 点此下载全文 |
| 宋 红 邓景贵 陶 希 陈美娟 |
| 湖南省马王堆医院康复医学科，长沙，410016 |
| 基金项目： |
| DOI： |
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| 摘要
目的：探讨踏车运动对老年稳定型心绞痛患者的影响。
方法：141例老年稳定型心绞痛患者随机分成治疗组（68例）和对照组（73例），治疗组进行踏车运动和常规药物治疗，对照组实行常规药物治疗，疗程4个月。使用放射免疫法检测实验前后血浆TXA2及免疫比浊法检测CRP、LDL-C和HDL-C水平，监测实验过程中心率及血压变化，比较实验前后两者有无差异，并调查对比两组实验结束后1月内心绞痛的发生率。
结果：治疗组有2例患者因不能耐受退出研究。对照组治疗后血浆CRP、TXA2和LDL-C水平分别下降58.30%、45.64%和36.04%，HDL-C升高0.71%；治疗组治疗后血浆CRP、TXA2和LDL-C水平分别下降65.47%、38.29%和36.18%，HDL-C升高2.11%；治疗组较对照组CRP下降明显，差异有显著性意义（P＜0.05）；但两组间TXA2、LDL-C下降及HDL-C升高无明显差异（P＞0.05）。治疗前后两组间血压、心率变化无明显差异。两组治疗后均进行随访1个月，治疗组（5/66）较对照组(16/73)心绞痛发生率明显减少，差异有显著性意义（P＜0.05）。
结论：踏车运动能明显降低老年稳定型心绞痛患者心绞痛发生率，其机制可能与降低CRP表达有关。 |
| 关键词：踏车运动 稳定型心绞痛 老年 C反应蛋白 |
| The effect of treadmill exercise on the prognosis of elderly patients with stable angina pectoris/ Download Fulltext |
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| Mawangdui Hospital of Hunan Province, Changsha, 410016 |
| Fund Project: |
| Abstract: |
| Abstract
Objective: To study the effect of treadmill exercise on the prognosis of elderly patients with stable angina pectoris (SAP) patients.
Method: One hundred and forty-one SAP patients were divided randomly into treadmill exercise group (68 cases) and control group (73 cases). The patients in treadmill exercise group received treadmill and conventional drug treatment for 4 months, and those in control group received routine drug treatment only. The differences on levels of plasma CRP, TXA2, LDL-C and HDL-C were defected between before and after experiment; the diversities of heart rate and blood pressure were monitored in experiment process and the differences between before and after experiment were compared; and the incidences of angina pectoris of two groups in 1 month after experiment were investigated.
Result: Two patients in treadmill exercise group signed off the research because of intolerance. The levels of plasma CRP, TXA2 and LDL-C in control group after treatment decreased by 58.30%, 45.64% and 36.04% respectively, but HDL-C elevated 0.71%; the levels of plasma CRP, TXA2 and LDL-C in treadmill exercise group after treatment decreased by 65.47%, 38.29% and 36.18% respectively, but HDL-C elevated 2.11%; the level of plasma CRP in treadmill exercise group decreased more significantly (P＜0.05) than that in control group, but the decrease of TXA2 and LDL-C and rise of HDL-C had less significant differencely in two groups (P＞0.05). The heart rate and blood pressure had less significant difference between two groups before and after treatment. The incidence of angina pectoris in treadmill exercise group (5/66) was less (P＜0.05) than that in control group (16/73) when the two groups were followed up after treatment in 1 month.
Conclusion: Treadmill exercise could significantly reduce the incidence of angina pectoris of elderly SAP patients, its mechanism maybe concerned with the decreasing of expression of plasma CRP. |
| Keywords:treadmill exercise stable angina pectoris the elderly C-reactive protein |
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