| 吴军发,胡永善,吴 毅,施爱萍,路微波,刘含秋.健康成人吞咽口腔期的功能磁共振成像研究[J].中国康复医学杂志,2013,28(9):789~793 |
| 健康成人吞咽口腔期的功能磁共振成像研究 点此下载全文 |
| 吴军发 胡永善 吴 毅 施爱萍 路微波 刘含秋 |
| 复旦大学附属华山医院康复医学科，复旦大学上海医学院康复医学系，上海，200040 |
| 基金项目： |
| DOI： |
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| 摘要： |
| 摘要
目的：探讨健康成人吞咽口腔期的神经控制机制。
方法：通过血氧水平依赖性磁共振脑功能成像(BOLD-fMRI) 技术，研究8位健康志愿者叩齿和和舌尖沿上腭由前向后滑动时脑激活情况，用SPM5图像处理软件处理功能磁共振成像资料。
结果：叩齿时，激活区主要分布于双侧中央前回、邻近的双侧岛盖、双侧辅助运动区；舌尖沿上腭由前向后滑动时，激活区主要分布在双侧中央前回、邻近的双侧岛盖、双侧辅助运动区、双侧小脑后叶结节、双侧小脑后叶下半月小叶。叩齿和舌尖沿上腭由前向后滑动共同激活区位于双侧的中央前回、邻近的双侧岛盖和双侧辅助运动区。
结论:双侧的中央前回、邻近的双侧岛盖及双侧的辅助运动区是吞咽口腔期的神经控制网络的一部分。 |
| 关键词：叩齿 舌尖运动 吞咽障碍 功能磁共振成像 |
| A functional magnetic resonance imaging study of oral phase of swallowing in healthy humans Download Fulltext |
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| Dept. of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040 |
| Fund Project: |
| Abstract: |
| Abstract
Objective:To explore the neurophysiology mechanism of oral phase of swallowing in healthy humans.
Method：During eight healthy volunteers were knocking their teeth and moving the tongue tip backwards along the palate, the activation pattern of cortex was showed with blood oxygen level dependent-functional magnetic resonance imaging(BOLD-fMRI).Image data were analysed by microsoft SPM5.
Result：When subjects were knocking the teeth,bilateral precentral gyruses,adjacent rolandic operculums (ROs) and supplementary motor areas(SMAs) were significantly activated. When subjects were moving the tongue tip backwards along the palate,significant activations were observed in bilateral precentral gyruses, adjacent ROs and SMAs,cerebellum tuber and cerebellum inferior semi-lunar lobule. The common activated areas during knocking the teeth and moving the tongue tip backwards were located at bilateral precentral gyruses, odjacent ROs and SMAs.
Conclusion：Bilateral precentral gyruses and adjacent ROs and SMAs are parts of the neural network of oral phase of swallowing. |
| Keywords:knocking the tooth moving tongue tip dysphagia functional magnetic resonance imaging |
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