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李 霞,徐守宇,解光尧.单侧踝背屈等长运动对双侧大脑皮质的影响[J].中国康复医学杂志,2013,28(11):996~1000
单侧踝背屈等长运动对双侧大脑皮质的影响    点此下载全文
李 霞  徐守宇  解光尧
浙江中医药大学附属第三医院,杭州市滨江区滨文路548号,310005
基金项目:浙江省教育厅科研项目资助(Y201223514);浙江中医药大学科研项目(200712)
DOI:
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摘要:
      摘要 目的:利用fMRI技术研究人体单侧主动踝背屈时双侧脑功能区激活情况,为力量训练交叉迁移的中枢机制提供理论依据,并为进一步临床康复应用提供理论支持。 方法:选取8名健康青年男性右利腿志愿者,以右踝关节背屈主动用力最大等长收缩为刺激模式,采用组块设计,使用1.5T磁共振全身扫描仪进行fMRI数据采集,利用SPM5软件进行数据分析和脑功能区定位。 结果:右踝背屈主动运动主要激活脑区为双侧初级躯体运动区、双侧次级躯体感觉区、双侧运动前区、双侧运动辅助区、双侧小脑、双侧扣带回及对侧初级躯体感觉区。 结论:单侧踝背屈主动运动引起双侧大脑皮质多个运动相关皮质的激活,说明主动运动引起的交叉迁移现象可能存在大脑皮质机制,支持皮质参与的神经机制学说,也为进一步将交叉迁移效果应用到临床提供了理论依据。
关键词:交叉迁移  功能性磁共振成像  踝背屈
The impact of unilateral voluntary ankle isometric dorsiflexion on bilateral cerebral cortex activation    Download Fulltext
The Third Affiliated Hospital of Zhejiang Chinese Medial University, Hangzhou,310005
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Abstract:
      Abstract Objective: To investigate bilateral cerebral cortex activation during unilateral voluntary ankle isometric dorsiflexion by using fMRI, to provide evidence for the underlying central mechanisms of strength training cross education and practice of clinical rehabilitation. Method: Eight right-footed healthy subjects volunteered for the study. During the maximum isometric dorsiflexion of the right ankle, fMRI images of cerebral cortex activation were obtained. A block design was used for the inspection. The fMRI was performed on a 1.5T whole body MRI scanner. SPM5 was used to process data and localize functional areas. Result: For voluntary contraction task, significant activations were observed in the bilateral primary motor cortex, bilateral secondary somatosensory cortices, bilateral premotor cortex, bilateral supplementary motor area, bilateral cerebellum, bilateral cingulated gyrus and contralateral primary sensory area. Conclusion: Multiplemotor areas in bilateral cerebral cortex were activated in the voluntary tasks. Cortical mechanisms may be involved in voluntary cross education, which provide experimental evidence and offer a new way for clinical rehabilitation practice in requiring cases.
Keywords:cross education  functional magnetic resonance imaging  ankle dorsiflexion
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