| 汪 洁,吴东宇,宋为群,袁 英.双额叶在线经颅直流电刺激对失语症图命名的作用[J].中国康复医学杂志,2014,29(1):31~35 |
| 双额叶在线经颅直流电刺激对失语症图命名的作用 点此下载全文 |
| 汪 洁 吴东宇 宋为群 袁 英 |
| 首都医科大学宣武医院康复医学科，北京，l00053 |
| 基金项目：国家自然科学基金资助课题（30600186，81171011，81272173）；首都临床特色应用研究（Z121107001012144） |
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| 摘要
目的：探查左侧Broca区阳极和Broca右侧对应区阴极经颅直流电刺激（tDCS）对脑卒中后失语症患者图命名是否有促进作用，两者的促进作用是否有差异。
方法：对29例额叶及基底核区脑卒中后（2—12个月）失语症患者进行图命名检查的同时，实施在线左侧Broca区阳极、Broca右侧对应区阴极tDCS，其检查结果与假刺激图命名检查结果对照。三种实验条件间隔时间≥24h。左右侧tDCS随机实施。
结果：尽管部分患者显示右侧对应区阴极tDCS可以提高图命名成绩，但是只有左侧Broca区阳极tDCS可以显著改善失语症患者的图命名能力（P＜0.05）。
结论：增强左Broca区皮质的兴奋性，可以促进失语症患者图命名能力的改善；左Broca区及其周围区在脑卒中后失语症患者的语言恢复中仍起着重要作用。 |
| 关键词：失语症 经颅直流电刺激 脑卒中 Broca区 |
| Effects of transcranial direct current stimulation over bilateral frontal gyrus on picture naming in aphasia Download Fulltext |
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| Dept. of Rehabilitation Medicine, Xuanwu Hospital of Capital Medical University, Beijing, 100053 |
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| Abstract: |
| Abstract
Objective: To investigate the effects of transcranial direct current stimulation (tDCS) over bilateral frontal gyrus on picture naming in aphasia.
Method: Twenty-nine aphasics with left frontal gyrus or basal ganglia lesion 2—12 months post-stroke undertook a picture-naming test with on-line anodal tDCS over the left Broca's area and on-line cathodal tDCS over the right Broca's homologue respectively. The test results of these two conditions were compared with that of sham stimulation respectively. The interval among the three conditions was 24h. The left and right frontal gyri tDCS were randomly administered.
Result: The picture-naming score improved significantly only in the condition of anodal tDCS over the left Broca's area compared with sham stimulation group (P＜0.05), although some patients showed improvement during cathodal tDCS over the right Broca's homologue.
Conclusion: Improvement of the picture naming in aphasia can be yielded by increasing the excitability of left Broca's area. The left Broca's area and its peripheral areas play a very important role on the language recovery in aphasia after stroke. |
| Keywords:aphasia transcranial direct current stimulation stroke Broca's area |
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