| 赵玄骥,王云亭,王荣国,刘守尧,于占歌.电针对家兔急性钝器伤后高凝状态分子标志物D-二聚体和凝血酶-抗凝血酶复合物的影响[J].中国康复医学杂志,2015,(12):1208~1211 |
| 电针对家兔急性钝器伤后高凝状态分子标志物D-二聚体和凝血酶-抗凝血酶复合物的影响 点此下载全文 |
| 赵玄骥 王云亭 王荣国 刘守尧 于占歌 |
| 北京中医药大学，北京，100029 |
| 基金项目：国家自然科学基金资助项目（81173343） |
| DOI： |
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| 摘要： |
| 摘要
目的：探讨电针对家兔急性钝器伤后D-二聚体（D-Dimer）和凝血酶-抗凝血酶复合物（thrombin-antithrombin complex，TAT）的影响作用。
方法：将18只新西兰大白兔随机分为3大组，即空白组、模型组、电针组；每组6只动物。电针组在常规治疗的基础上，于伤后24h开始电针治疗。在造模前、造模后第1天、第4天、第7天分别对各组动物进行耳中动脉采血，测定D-Dimer和TAT的含量。
结果：造模后第1天，模型组和电针组的D-Dimer、TAT的含量高于空白组（P＜0.05）；造模后第4天，模型组的D-Dimer、TAT含量高于电针组（P＜0.05），而电针组又高于空白组（P＜0.05）；造模后第7天，模型组和电针组的D-Dimer、TAT的含量呈下降趋势，但仍高于空白组（P＜0.05）。
结论：电针弱刺激可以有效减少家兔急性钝器伤后D-Dimer和TAT的升高，防止高凝状态的形成。 |
| 关键词：电针 高凝状态 D-二聚体 凝血酶-抗凝血酶复合物 |
| Effects of electroacupuncture on D-Dimer and thrombin-antithrombin complex of molecular markers of hypercoagulable state in rabbits after acute blunt trauma Download Fulltext |
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| Beijing University of Chinese Medicine, Beijing, 100029 |
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| Abstract: |
| Abstract
Objective: To investigate the influence of electroacupuncture for rabbits with acute blunt injury of D-Dimer and thrombin-antithrombin complex (TAT).
Method: The 18 New Zealand white rabbits were randomly divided into three major groups, namely the blank group, model group and electroacupuncture group; and each group of 6 rabbits. In electroacupuncture group on the basis of conventional therapy, 24h after injury electroacupuncture treatment began. Before modeling and after modeling 1d, 4d, 7d respectively, in each group arterial blood were adopted from rabbits ears to measure the contents of D-Dimer and TAT.
Result: On the 1st day after modeling, in model group and electroacupuncture group the contents of D-Dimer and TAT were higher than that of blank group (P＜0.05). On the 4th day after modeling, the contents of D-Dimer and TAT in model group were higher than those in electroacupuncture group (P＜0.05), and in acupuncture group those were higher than that in blank group (P＜0.05). On the 7th in model group and electroacupuncture group the contents of D-Dimer and TAT decreased, but still higher than that in blank group (P＜0.05).
Conclusion: Electroacupuncture of weak stimulation can effectively reduce the increase of D-Dimer and TAT in rabbits after acute blunt injury, and prevent the formation of hypercoagulable state. |
| Keywords:electroacupuncture hypercoagulable state D-Dimer thrombin-antithrombin complex |
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