| 李秀明,谢 青,鲍 勇,计海彪.预测基底核性失语患者早期言语功能结局的研究[J].中国康复医学杂志,2016,(6):659~663 |
| 预测基底核性失语患者早期言语功能结局的研究 点此下载全文 |
| 李秀明 谢 青 鲍 勇 计海彪 |
| 上海交通大学医学院附属瑞金医院北院康复医学科，上海，201801 |
| 基金项目： |
| DOI： |
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| 摘要： |
| 摘要
目的：通过观察分析卒中后单侧基底核性失语患者的CT表现,探讨CT评分与患者言语功能早期恢复的相关性。
方法：前瞻性收集了2013年12月—2015年6月入住我院的基底核区卒中患者89例，分别在发病后的第3个月、第6个月进行随访。基底核性失语症患者的CT评分方法——卒中改变发生在尾状核、豆状核、内囊、外囊、放射冠这5个区域中；每累及一个区域得1分。按照CT评分结果分为5个组。结合患者临床特征，选择性别、年龄、病因（出血性、缺血性）、卒中病灶的位置、发病后24h—72h的CT评分、汉语失语成套测验的4项（谈话、理解、复述、命名）评分作为观察指标。
结果：5组组内两个时间点的言语功能评分比较用Mann-Whitney法检验，除CT评分1分组，患者卒中后6个月的谈话、理解、复述、命名能力均较入组时有显著改善（P＜0.01）；采用Spearman相关分析研究CT评分与言语功能各项评分之间的关系，发现CT评分与上述各项评分在卒中后3个月、6个月均成显著性负相关（P＜0.01）。以ABC评分为参照，用ROC曲线进行诊断性评价，当CT评分≤2分时，ABC评分的谈话、理解、复述、命名各项结果的预后较好。
结论：卒中后单侧基底核性失语CT评分的灵敏度及特异度较高，该评分对单侧基底核性失语的早期预后评估有一定的指导意义。 |
| 关键词：基底核性失语 CT评分 言语功能结局 预测因素 |
| A study on CT scan evaluation in early prognosis of basal ganglia aphasia Download Fulltext |
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| Dept. of Rehabilitation Medicine, the North Ruijin Hospital, Jiaotong University, Shanghai, 201801 |
| Fund Project: |
| Abstract: |
| Abstract
Objective: To observe and analyze the CT scan features of the patients with unilateral basal ganglia aphasia after stroke and to explore the correlation between the CT score and the early recovery of speech function.
Method: A study was conducted, including 89 patients with diagnosis of basal ganglia stroke admitted for rehabilitation in rehabilitation medicine department, from December 2013 to June 2014. Follow up was performed at third and sixth months after the onset of the disease. Based on if there is lesion at caudle nucleus, entiform nucleus， capsula interna， capsula interna，corona radiate on CT scan, patients were divided into group with 1—5 points, one lesion counts as one point. Following variables were collected such as medical history, gender, age, etiology (hemorrhagic or ischemic), lesion location of stroke, CT score 24h—72h after the onset, 4 items (conversation, understanding, repetition, naming) of aphasia battery of Chinese score(ABC).
Result: Speech function of different CT score groups at two points were compared with the Mann-Whitney test. In addition to the group of 1 score, a significant speech improvement (conversation, understanding, repetition, naming ) was observed at 6 months after stroke (P<0.01). The correlation between the CT Score and items of speech function was measured by means of the Spearman correlation，a significant negative correlation was observed at 3 months and 6 months after stroke (P<0.01). The groups of CT Score ≤2 showed better conversation, understanding, repetition, naming outcome by constructing ROC curves of the ABC.
Conclusion: The CT score of unilateral basal ganglia aphasia after stroke showed better sensitivity and specificity, in early prognosis of the patients with unilateral basal ganglia aphasia. |
| Keywords:basal ganglia aphasia CT score language function outcome predictor |
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