| 陈树耿,束小康,贾 杰.基于闭环脑机接口的脑卒中患者的手功能康复研究[J].中国康复医学杂志,2016,(11):1189~1194 |
| 基于闭环脑机接口的脑卒中患者的手功能康复研究 点此下载全文 |
| 陈树耿 束小康 贾 杰 |
| 复旦大学附属华山医院康复医学科，上海静安区，200040 |
| 基金项目：国家高技术研究发展计划（863计划）项目资助（SS2015AA020501） |
| DOI： |
| 摘要点击次数: 1558 |
| 全文下载次数: 2120 |
| 摘要： |
| 摘要
目的：探讨基于运动想象（MI）的闭环式脑机接口（BCI）在脑卒中后手功能康复中的大脑运动皮质激活状态评估与治疗效果。
方法：将6例有上肢手功能障碍的脑卒中患者随机分为MI-BCI组（3例）和MI组（3例），均接受常规的康复治疗，MI-BCI组进行为期1个月，每周3次的闭环BCI的康复训练，MI组为同等量的运动想象训练。在治疗前和1个月的治疗结束后，分别对两组患者进行BCI脑电评估，针对上肢手进行改良Ashworth评分（MAS）、上肢Fugl-Meyer评估（FMA）和运动功能状态量表（MSS）评分，MI-BCI组在治疗结束后1周再进行一次脑电评估。
结果：经过1个月的康复训练，两组患者在FMA、MSS评分上较治疗前均有所提高，MI-BCI组较MI组在脑区激活上更为明显。
结论：基于运动想象的闭环式脑机接口康复训练可促进脑卒中患者大脑的脑区激活，从而有利于其皮质重塑，促进上肢及手功能康复疗效的提高。 |
| 关键词：脑机接口 闭环 手功能康复 脑卒中 |
| Research on closed-loop-based brain computer interface for hand rehabilitation in stroke patients Download Fulltext |
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| Dept. of Rehabilitation Medicine, Shanghai Huashan Hospital,200040 |
| Fund Project: |
| Abstract: |
| Abstract
Objective：To explore the effect of closed-loop-based brain computer interface (BCI) on the assessment of the active state of motor cortex and treatment for hand rehabilitation in stroke patients.
Method：Six stroke patients with dysfunction in the upper limb and hand were randomly divided into MI-BCI group (n=3) and MI group (n=3). Both groups received the routine rehabilitation. BCI group was treated with BCI rehabilitation for 1 months, 3 times per week while MI group received MI training with the same frequency. BCI-based EEG, Modified Ashworth assessment(MAS), Fugl-Meyer motor assessment(FMA) and motor state scale(MSS) were evaluated for two groups before treatment and after 1 month therapy. BCI-based EEG was recorded again at 1 week after the completion of treatment.
Result：After 1 month MI-BCI training, the scores of FMA and MSS were improved than that before therapy for two groups. Moreover, the cortex activation in the MI-BCI group patients was more evident than that in the MI group.
Conclusion：Closed-loop motor imagery-based BCI training can promote the activation and remodeling in cortex and then improve the function of hand for stoke patients. |
| Keywords:brain computer interface closed-loop hand rehabilitation stroke |
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