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张 雷,彭继海,张鸣生.慢性阻塞性肺病肌肉功能与肺功能的相关性[J].中国康复医学杂志,2017,(1):44~47
慢性阻塞性肺病肌肉功能与肺功能的相关性    点此下载全文
张 雷  彭继海  张鸣生
广东省人民医院,广东省医学科学院,广州,510080
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摘要:
      摘要 目的:探讨慢性阻塞性肺病患者肌肉功能与肺功能的相关性。 方法:87例慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)患者进行肘屈伸、膝屈伸的等速肌力测试,记录60°/s和180°/s角速度时每次屈伸运动的峰力矩。 结果:肘、膝屈伸力量与运动后心率、呼吸频率和6min步行试验呈正相关,与运动后血氧饱和度呈负相关,伸膝疲劳性与6min步行试验、运动心率、运动后呼吸频率呈负相关,与运动后血氧饱和度呈正相关。肘、膝屈伸力量与舒张后一秒用力呼气容积(forced expiratory volume in one second, FEV1) (r=0.297—0.369,P<0.05)、最大呼气流量(peak expiratory flow,PEF)舒张后(r=0.19,P>0.05;r=0.254—0.313,P<0.05)、深吸气量(inspiratory capacity,IC)舒张后(r=0253—0.312,P<0.05)、6min步行测试后IC(r=0.288—0.342,P<0.05)呈正相关。 结论:COPD患者肌肉功能减弱可能是全身性的,与过度充气存在一定关系。
关键词:慢性阻塞性肺病  肺功能  肌肉功能  等速肌力测试
The relationship between lung function and muscular function In COPD    Download Fulltext
Department of Rehabilitation Medicine, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou,510080
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Abstract:
      Abstract Objective: To investigate the relationship between lung function and muscular function in COPD. Method: 87 patients with COPD were recruited. Isokinetic strength of flexor and extensor of elbow and knee was evaluated with Isomed 2000 isokinetic dynamometer. The peak torque of flexor and extensor was recorded at angle velocity of 60°/s and 180°/s. Result: The strength of flexor and extensor of elbow and knee was positive related to heart rate, respiratory frequency and distance in 6 minute walk test, but inversely negatively related to blood oxygen saturation after exercise. In contrast, the fatigue of knee extension was inversely related to heart rate, respiratory frequency and distance in 6 minute walk test, and positively related to blood oxygen saturation after exercise. The strength of flexor and extensor of elbow and knee was positively related to forced expiratory volume in first second(r=0.297—0.369,P<0.05), peak expiratory flow before and after bronchodilatation (r=0.19,P>0.05; r=0.254—0.313,P<0.05), inspiratory capacity (r=0253—0.312,P<0.05) and that after 6 minutes walk test(r=0.288—0.342,P<0.05). Conclusion: The muscular function decreasing in COPD may be systematically, and may be related to hyperinflation.
Keywords:chronic obstructive pulmonary disease  lung function  muscular function  isokinetic test
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