| 蒋玉尔,林 枫,钟丽娟,江钟立.同类图片命名中信息处理的脑磁图研究[J].中国康复医学杂志,2020,(7):801~807 |
| 同类图片命名中信息处理的脑磁图研究 点此下载全文 |
| 蒋玉尔 林 枫 钟丽娟 江钟立 |
| 南京医科大学第一附属医院，南京，210029 |
| 基金项目：国家自然科学基金资助项目（81672255）；江苏省高校哲学社会科学优秀创新团队建设项目资助（2017STD006）；江苏高校优势学科建设工程资助项目（JX10231801） |
| DOI：10.3969/j.issn.1001-1242.2020.07.007 |
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| 摘要： |
| 摘要
目的：应用脑磁图（MEG）检查，探讨同类图片命名任务中大脑的时空激活模式，为临床言语治疗提供依据。
方法：选取健康成年右利手受试者10例（男性5例，女性5例）。实验任务为出声命名相同类别的图片。应用磁共振（MRI）获取个体大脑结构图像，通过脑磁图（MEG）检测图片命名过程中，全脑在不同时间窗内的激活水平。
结果：在特征提取和语义编码时间窗内，视觉系统和腹侧颞叶联合系统的激活水平显著高于内侧默认模式系统（P<0.01），其中腹侧颞叶联合系统的左侧半球的激活水平显著高于右侧半球（P<0.05）；在语音编码及发音发声时间窗内，腹侧颞叶联合系统、额-顶系统、扣带回-岛盖系统、注意系统、视觉系统以及听觉系统的激活水平均显著高于内侧默认模式系统（P<0.01），其中腹侧颞叶联合系统、额-顶系统和听觉系统的左侧半球的激活水平显著低于右侧半球（P<0.05）。
结论：同类图片命名任务中，大脑随时间出现偏侧化优势激活。左偏侧化出现在信息处理过程的前期，与视觉特征提取和语义加工有关；右偏侧化出现在信息处理过程的后期，与语音加工有关。语义腹侧流和语音背侧流的时空分离现象为临床精准治疗提供了依据。 |
| 关键词：图片命名 信息处理 脑磁图 功能系统 偏侧化 |
| An MEG study of information processing during related picture naming task Download Fulltext |
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| The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029 |
| Fund Project: |
| Abstract: |
| Abstract
Objective：Using MEG to examine the spatiotemporal activation patterns of the brain during related picture naming task to provide evidence for clinical speech therapy.
Method：Ten healthy right-handed adults were selected (5 males and 5 females) for overt naming of related pictures.The brain structure of the individual was acquired by MRI， and the activation of the whole brain in different time windows was recorded by MEG.
Result：In the time windows of feature extraction and semantic coding， the activation levels in visual system and ventral temporal association system were significantly higher than that in medial default mode system (P<0.01)， and the activation levels in the left hemisphere of temporal association system were significantly higher than that in the right hemisphere(P<0.05). In the stage of phonologic coding and articulation， the activation levels in ventral temporal lobe associated system， frontal-parietal system， cingulo-opercular system， attention system， visual system and auditory system were significantly higher than that in medial default mode system (P<0.01)， and the activation levels in the left hemisphere of temporal association system， frontal-parietal system and auditory system were significantly lower than that in the right hemisphere (P<0.05).
Conclusion：The dominant activation foci for semantic and phonologicprocessing took place in different brain regions in the related picture naming task. During semantic processing， the left hemisphere especially in the ventral temporal pathway was activated for a long time， which may promote semantic coding. During phonologic processing， right-lateralization especially in the right frontotemporal lobe appeared， which related with speech coding and vocalization.The spatiotemporal separation of semantic ventral stream and speech dorsal stream provides a basis for clinical precise treatment. |
| Keywords:picture naming information processing magnetoencephalography functional system laterality |
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