| 高修明,项 洁,滕晓晓,陈珍珍,江钟立,林 枫.胼胝体分离综合征神经心理学特征的诊疗流程及应用[J].中国康复医学杂志,2020,(10):1198~1202 |
| 胼胝体分离综合征神经心理学特征的诊疗流程及应用 点此下载全文 |
| 高修明 项 洁 滕晓晓 陈珍珍 江钟立 林 枫 |
| 徐州医科大学附属医院康复科；徐州医科大学医技学院，徐州，221000 |
| 基金项目：徐州市临床技术骨干研修计划项目（2018211009） |
| DOI：10.3969/j.issn.1001-1242.2020.10.008 |
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| 摘要： |
| 摘要
目的：本研究拟通过标准的诊断流程，分析胼胝体分离综合征（CDS）的神经心理学特征，为临床诊疗提供客观依据。
方法：回顾性分析8例CDS患者的病因﹑神经心理学表现及影像学特点。
结果：影像学提示患者均为缺血性卒中，病灶均累及胼胝体，其中膝部6例﹑体部8例﹑压部4例；患者均伴有认知障碍，MoCA评分为（19.00±4.11），均<26分；神经心理学表现复杂多样，评估显示偏瘫（8/8例）﹑异己手综合征（8/8例）﹑失语症（3/8例）﹑触觉失认（4/8例）﹑失用症（5/8例）﹑失读症（4/8例）﹑失写症（4/8例）﹑偏侧忽略（3/8例）﹑精神障碍（4/8例）。
结论：CDS临床表现和神经心理学特征复杂多变，标准的评估流程有助于明确诊断，为临床诊疗提供可靠依据。 |
| 关键词：胼胝体分离综合征 发病机制 神经心理学 |
| Diagnosis and treatment process of neuropsychological characteristics of callosal disconnection syndrome and its application Download Fulltext |
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| Medical Technology School of Xuzhou Medical University， the Affiliated Hospital of Xuzhou Medical University， Xuzhou， Jiangsu， 221000 |
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| Abstract: |
| Abstract
Objective： To summarize the neuropsychological characteristics of callosal disconnection syndrome (CDS) with standard diagnostic process， and to provide the basis for clinical diagnosis and treatment.
Method： A retrospective analysis was made of the etiologic factors， clinical manifestations， neuropsychological characteristics and prognosis of 8 CDS patients.
Result： Imaging findings suggested that all patients had ischemic stroke， and the lesions involved corpus callosum all， of which 6 were at the genu， 8 were at the body， and 4 were at the splenium， the MoCA score was (19.00±4.11)， all <26 points. The neuropsychological manifestations were complex and diverse， including limb hemiplegia (8/8)， Alien hand syndrome (8/8)， aphasia (3/8)， tactile agnosia (4/8)， apraxia (5/8)， dyslexia (4/8)， agraphia (4/8)， hemispatial neglect(3/8)， and mental disorders (4/8).
Conclusion： The clinical manifestations and neuropsychological manifestations of CDS are diverse， and the standard diagnostic process is helpful to make diagnosis and provide a reliable basis for clinical treatment. |
| Keywords:callosal disconnection syndrome pathogenesis neuropsychology |
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