| 刘 罡,贾晋瑄,曹 悦,田 闪,沈雪彦,陆蓉蓉,陈 颖,谢鸿宇,余克威,吴军发,吴 毅.短时程非强直性低频超强神经电刺激对脑卒中患者脊髓运动神经元兴奋性的影响[J].中国康复医学杂志,2021,(5):526~532 |
| 短时程非强直性低频超强神经电刺激对脑卒中患者脊髓运动神经元兴奋性的影响 点此下载全文 |
| 刘 罡 贾晋瑄 曹 悦 田 闪 沈雪彦 陆蓉蓉 陈 颖 谢鸿宇 余克威 吴军发 吴 毅 |
| 复旦大学附属华山医院康复医学科，上海市，200040 |
| 基金项目：国家重点研发计划（2018YFC2001700）；上海市卫计委项目（20154Y0101）；上海市科学技术委员会项目（17411953900） |
| DOI：10.3969/j.issn.1001-1242.2021.05.004 |
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| 摘要： |
| 摘要
目的：研究非强直性低频超强神经电刺激对脊髓运动神经元兴奋性的影响，为完善脑卒中后外周神经电刺激治疗参数提供参考。
方法：分别比较脑卒中患者和健康人群在0.5Hz低频F波检测中最初5次和最终5次超强刺激下F波次数，潜伏期和F波幅/M波幅（F/M）的变化情况。F波检测通过刺激腓骨头下腓总神经完成，记录肌肉为胫骨前肌和腓骨肌。
结果：在脑卒中患者和健康人群，超强低频腓总神经电刺激前后胫骨前肌和腓骨肌F波出现次数、F/M值、潜伏期均无明显变化。
结论：短时程非强直性低频超强周围神经电刺激不改变脑卒中患者和健康人群脊髓运动神经元的兴奋性；在超强刺激强度下，不同刺激频率可能对脊髓运动神经元兴奋性产生差异性影响。 |
| 关键词：神经兴奋性 脊髓 电刺激 低频 脑卒中 |
| Short term non-tetanic low frequency supramaximal neural electrical stimulation does not alter the post-stroke excitability of spinal motor neuron Download Fulltext |
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| Huashan Hospital，Fudan University，Shanghai，200040 |
| Fund Project: |
| Abstract: |
| Abstract
Objective：To study the effect of non-tetanic low frequency(LF) supramaximal neural electrical stimulation (NES) on the excitability of spinal motor neuron and to provide reference for improving the parameters of peripheral nerve electrical stimulation after stroke.
Method： The occurrence number of F wave， latency， and F wave amplitude/M wave amplitude(F/M) were recorded in stroke patients and healthy participants， and the difference between the first five and last five stimuli were analyzed. The stimulation frequency of F wave examination was 0.5Hz with a total of 20 times stimuli. F wave was detected by stimulating common peroneal nerves just beneath the fibular head， and the recorded muscles were tibialis anterior(TA) and peroneus muscle(PN).
Result： In both healthy participants and stroke patients， there was no significant change in occurrence number， F/M/ and latency after LF supramaximal NES.
Conclusion： The excitability of spinal motor neurons is not affected by short term non-tetanic LF supramaximal peripheral nerve stimulation. The variation of the spinal motor excitability may depend on the frequency in supramaximal NES. |
| Keywords:neural excitability spinal cord motor neuron electrical stimulation low frequency stroke |
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