| 傅彩峰,高 朝,刘梦姣,吕少萍,刘佐莹,林晓燕,王可欣.不同强度的高频重复经颅磁刺激对脑梗死早期患者上肢功能的影响[J].中国康复医学杂志,2024,(9):1304~1309 |
| 不同强度的高频重复经颅磁刺激对脑梗死早期患者上肢功能的影响 点此下载全文 |
| 傅彩峰 高 朝 刘梦姣 吕少萍 刘佐莹 林晓燕 王可欣 |
| 青岛大学附属青岛市中心医院康复医学科，山东省青岛市，266042 |
| 基金项目：青岛市医疗卫生重点学科建设项目；青岛市医疗卫生优秀人才培养项目；青岛市2022年度医药卫生科研指导项目（2022-WJZD090） |
| DOI：10.3969/j.issn.1001-1242.2024.09.009 |
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| 摘要： |
| 摘要
目的：观察不同强度高频重复经颅磁刺激（high-frequency repetitive transcranial magnetic stimulation， HF-rTMS）对脑梗死恢复早期患者上肢功能障碍恢复的影响。
方法：选取60例脑梗死恢复早期患者，采用随机数字表法分为HF-rTMS 80%RMT组、100%RMT组和假刺激组，每组各20例。三组患者均给予基础治疗（药物治疗及常规康复训练），在此基础上分别给予不同强度的HF-rTMS治疗。记录治疗前及治疗4周后3组患者的Fugl-Meyer上肢运动功能评定（Fugl-Meyer assement-upper extremity， FMA-UE）和改良Barthel 指数（modified Barthel Index， MBI）分值，检测运动诱发电位（motor evoked potential， MEP）潜伏期，计算中枢运动传导时间（central motor conduction time， CMCT），测量患侧大脑中动脉（middle cerebral artery， MCA）血流速度。
结果：治疗前，3组患者的FMA-UE评分、MBI评分、MEP潜伏期、CMCT及MCA血流速度均无显著性差异（P＞0.05）。治疗4周后，3组患者的上述指标均较治疗前提高，具有显著性差异（P＜0.05）；其中80%RMT组、100%RMT组指标改善均较假刺激组显著（P＜0.05）；除MBI外，100%RMT组各项指标改善最为显著（P＜0.05）。
结论：HF-rTMS可以改善脑梗死恢复早期患者上肢功能和日常生活能力，100%RMT HF-rTMS在提高功能、运动神经兴奋性，改善脑血流等方面较80%RMT更有优势。 |
| 关键词：脑梗死 高频重复经颅磁刺激 上肢功能 |
| Effects of different intensity of high frequency repetitive transcranial magnetic stimulation on upper limb function in patients with early post-stroke Download Fulltext |
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| Department of Rehabilitation Medicine， Affiliated Qingdao Central Hospital to Qingdao University， Qingdao， Shandong， 266042 |
| Fund Project: |
| Abstract: |
| Abstract
Objective： To evaluate the effects of high-frequency repetitive transcranial magnetic stimulation （HF-rTMS） of different intensities on the recovery of upper limb motor dysfunction in patients during the early recovery stage of cerebral infarction.
Method： Sixty patients with cerebral infarction at early recovery stage were randomly divided into the HF-rTMS 80% RMT group，the HF-rTMS 100% RMT group and the sham stimulation group，with 20 patients in each group. All three groups were also given basic treatment（medication and routine rehabilitation training）. Before and after 4 weeks treatment， the Fugl-Meyer Assessment-Upper extremity （FMA-UE） and Modified Barthel Index（MBI）, the latency of motor evoked potential （MEP）. central motor conduction time（CMCT） and blood flow velocity of the ipsilateral middle cerebral artery（MCA） were recorded.
Result： Before treatment， there were no significant differences in FMA-UE score, MBI score, MEP latency, CMCT and the blood flow velocity of MCA among the three groups（P>0.05）. After four weeks of treatment，the above indicators of the three groups were significantly higher than those before treatment（P<0.05）. Moreover， the improvement of the indicators in the 80%RMT group and 100%RMT group were significantly higher than those in the sham stimulation group（P<0.05）. Except for MBI score, the improvement in all indicators in the 100%RMT group were the most significant （P<0.05）.
Conclusion： HF-rTMS can improve upper limb function and activity of daily living during the early recovery stage of cerebral infarction. Compared with 80%RMT， 100% RMT HF-rTMS has more advantages in improving function, motor nerve excitability and cerebral blood flow. |
| Keywords:cerebral infarction high-frequency repetitive transcranial magnetic stimulation upper limb function |
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