| 唐芷晴,刘天昊,苏文龙,刘 影,韩凯月,李 慧,迟茜茜,张小年,张 皓.基于倾向性评分匹配分析间歇性θ波脉冲刺激对脑卒中后运动功能和日常生活活动的影响[J].中国康复医学杂志,2026,(8):1261~1267 |
| 基于倾向性评分匹配分析间歇性θ波脉冲刺激对脑卒中后运动功能和日常生活活动的影响 点此下载全文 |
| 唐芷晴 刘天昊 苏文龙 刘 影 韩凯月 李 慧 迟茜茜 张小年 张 皓 |
| 首都医科大学康复医学院，北京市，100068 |
| 基金项目：中国康复研究中心青年基金课题（2023ZX-Q3） |
| DOI：10.3969/j.issn.1001-1242.2026.08.010 |
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| 摘要： |
| 摘要
目的：基于回顾性研究数据分析间歇性θ波脉冲刺激（intermittent theta burst stimulation， iTBS）对住院脑卒中患者运动功能和日常生活活动（activities of daily living， ADL）的影响。
方法：回顾性收集2020年9月至2022年10月在中国康复研究中心神经康复科住院的208例脑卒中患者资料，根据是否接受过iTBS治疗分为iTBS组（n=73）和常规康复组（n=135），运用倾向性评分匹配（propensity score matched， PSM）分析对两组患者进行1∶1匹配，以平衡组间基线变量，并比较两组患者Fugl-Meyer运动功能评定量表（Fugl-Meyer motor assessment， FMA）评分、上肢FMA （FMA of the upper extremity， FMA-UE）评分、下肢FMA （FMA of the lower extremity， FMA-LE）评分、Barthel指数（Barthel index， BI）评分的改善情况。
结果：经PSM分析后共匹配出45对患者，与常规康复组相比，iTBS组患者的FMA评分变化值、FMA-UE评分变化值、FMA-LE评分变化值、BI评分变化值均显著改善（均P<0.05）。
结论：住院脑卒中患者在常规康复训练的基础上额外接受iTBS治疗可显著改善运动功能和ADL能力。 |
| 关键词：脑卒中 间歇性θ波脉冲刺激 运动功能 日常生活活动 倾向性评分匹配 |
| Effects of intermittent theta burst stimulation on motor function and activities of daily living in post-stroke patients: A propensity score matching analysis Download Fulltext |
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| School of Rehabilitation， Capital Medical University， Beijing， 100068 |
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| Abstract: |
| Abstract
Objective： To analyze the effects of intermittent theta burst stimulation （iTBS） on motor function and activities of daily living （ADL） in hospitalized stroke patients based on retrospective study data.
Method： Data of 208 stroke patients hospitalized in the Department of Neurorehabilitation at the China Rehabilitation Research Center between September 2020 and October 2022 were retrospectively collected. Patients were divided into the iTBS group（n=73） and the conventional rehabilitation group （n=135） according to whether they had received iTBS treatment. Propensity score matching（PSM） analysis was used to perform 1∶1 match to balance the baseline variables between groups. The changes of Fugl-Meyer motor assessment （FMA） score， including the upper extremity （FMA-UE) and the lower extremity （FMA-LE）, and the Barthel index （BI） score were compared between the two groups.
Result： A total of 45 pairs of patients were matched after PSM analysis. Compared with the conventional rehabilitation group， the changes in FMA score， FMA-UE score， FMA-LE score and BI score of iTBS group were significantly improved （all P<0.05）.
Conclusion：Adding iTBS to conventional rehabilitation training significantly improves motor function and ADL ability in hospitalized stroke patients. |
| Keywords:stroke intermittent theta burst stimulation motor function activities of daily living propensity score matched |
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