| 周晓兰,张志强.弱激光对兔失神经肌肉萎缩的防治作用[J].中国康复医学杂志,2010,25(8):725~728 |
| 弱激光对兔失神经肌肉萎缩的防治作用 点此下载全文 |
| 周晓兰 张志强 |
| 中国医科大学附属盛京医院康复科，沈阳，110021 |
| 基金项目： |
| DOI： |
| 摘要点击次数: 2060 |
| 全文下载次数: 1861 |
| 摘要： |
| 摘要
目的:观察弱激光对失神经肌萎缩的防治作用。
方法: 取健康雄性家兔30只，随机分为对照组（CON组），失神经肌萎缩组(DM组)和弱激光治疗+失神经肌萎缩组（LDM组），DM和LDM组采用家兔胫神经切断后制作失神经腓肠肌肌萎缩模型，进行HE染色及免疫组化研究，检测肌湿重，肌肉横断面面积及Bcl-2表达强度的差异。
结果:与DM组比较，LDM组腓肠肌湿重、肌肉横截面面积和Bcl-2表达均有明显差异（P<0.05）。
结论: 弱激光治疗可防治失神经引起的肌肉萎缩。 |
| 关键词：弱激光 失神经肌萎缩 腓肠肌 B细胞淋巴瘤/白血病-2（Bcl-2） |
| The influence of low-power laser irradiation on denervated myoatrophy in rabbits Download Fulltext |
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| Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110021 |
| Fund Project: |
| Abstract: |
| Abstract
Objective: To investigate the influence of low-power laser irradiation on denervated myoatrophy.
Method:Thirty rabbits were randomly divided into 3 groups, normal group（CON group），denervated myoatrophy group（DM group），and low-power laser irradiation plus denervated myoatrophy group(LDM group)， The right tibia nerves of rabbits in DM and LDM groups were cut off under aseptic conditions and were researched by HE staining and immunohistochemical techniques. The muscles were taken for measuring wet weight， investigating cross sectional area，as well as observing the expression of Bcl-2.
Result: There were statistical significances in all the data between the muscles in LDM group and DM group (P<0.05).
Conclusion: Low-power laser irradiation was a valuable treatment for preventing denervated muscle atrophy. |
| Keywords:low-power laser denervated muscle atrophy musculi gastrocnemius B cell lymphoma/leukemia-2（Bcl-2) |
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