| 方龙君,冯 珍.不同参数的正中神经电刺激对意识障碍患者促醒的影响[J].中国康复医学杂志,2021,(3):305~309 |
| 不同参数的正中神经电刺激对意识障碍患者促醒的影响 点此下载全文 |
| 方龙君 冯 珍 |
| 南昌大学第一附属医院康复医学科，江西省南昌市，330006 |
| 基金项目：国家自然科学基金资助课题（81660382，81260295) |
| DOI：10.3969/j.issn.1001-1242.2021.03.009 |
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| 摘要： |
| 摘要
目的：研究不同参数的正中神经电刺激（MNES）对意识障碍患者促醒的影响。
方法：选取160例格拉斯哥昏迷量表（GCS）≤8分的意识障碍患者，随机分为对照组（n=40）、试验1组（n=40）、试验2组（n=40）和试验3组（n=40）。对照组使用常规促醒方案治疗；试验组在此基础上联合MNES。试验1组电刺激脉宽参数为50μs，试验2组为200μs，试验3组为300μs。治疗时间为3个月。治疗前后分别采用GCS评分、改良国际昏迷恢复量表(CRS-R)和诱发电位检查评估患者意识状态水平。
结果：治疗结束后，各组GCS评分、CRS-R评分、N20潜伏期、V波潜伏期均较治疗前显著性改善（P<0.05）；试验各组优于对照组（P<0.05），试验3组优于试验1组和试验2组（P<0.05），试验1组和试验2组间无显著性差异（P>0.05）。
结论：正中神经电刺激脉宽参数为300μs时，能更好地促进意识障碍患者苏醒。 |
| 关键词：意识障碍 正中神经电刺激 康复 脉宽 |
| Effects of median nerve electrical stimulation with different parameters on patients with disorders of consciousness Download Fulltext |
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| Dept of Rehabilitation Medicine，The First Affiliated Hospital of Nanchang University，Jiangxi， Nanchang，330006 |
| Fund Project: |
| Abstract: |
| Abstract
Objective：To investigate the effects of median nerve electrical stimulation(MNES) with different parameters on patients with disorders of consciousness.
Method：One hundred patients with disorders of consciousness were randomly divided into control group (n=40)，experimental group 1 (n=40)， experimental group 2 (n=40) and experimental group 3 (n=40). The control group received routine wake-promoting methods， and the experimental groups received median nerve electrical stimulation with 50μs，100μs，200μs，300μs in sequence for 3 months.They were assessed with Glasgow coma scale (GCS)， coma recovery scale-revised(CRS-R) and evoked potentials before and after treatment.
Result：There was significant difference in the scores of GCS，CRS-R and latency of N20 and V wave (P<0.05)， that the experimental groups were better than the control group (P<0.05). The experimental group 3 was better than the experimental groups 1 and 2(P<0.05)， and no significant difference was found between the experimental groups 1 and 2(P>0.05).
Conclusion：MNES with 300μs could promote patients with disorder of consciousness to wake up optimally. |
| Keywords:consciousness disorders median nerve electrical stimulation rehabilitation pulse duration |
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